New Drug Target Found for Leukemia-linked Diseases

Contributing sentiments towards policy:

59% : Tax is crucial for viral gene expression, viral transmission and the development of cancer.
51% : " The study showed that KDR's role in the survival of HTLV-1-infected cells is connected to the viral protein called Tax.
44% : "KDR is not normally expressed in T cells, but Tax turns on its expression and hijacks its function, enabling it to stabilize and protect itself from degradation.
43% : They determined that blocking a class of enzymes called kinases, which regulates cellular functions, leads to cell death caused by the degradation of Tax, a protein essential for viral gene expression, viral transmission and survival of cells infected by HTLV-1.
42% : Cells that didn't express Tax weren't sensitive to KDR inhibition and didn't die.
37% : Suppression of KDR leads to the degradation of Tax and disrupts cancer-causing signaling pathways, leading to cell death.

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